CardOxyd

The development of CardOxyd takes into account the majority of the causes of the cardiovascular diseases.

The active components

• Arginine is an amino acid which endogenous synthesis is low at the level of our smoother cells.

Its role is however essential, since this amino acid is the precursor of the vasodilator mediator at the circulatory level, the nitric oxide, still called NO group, well known by the patients affected by angor and who are treated by the "Trinitrine" which releases NO from its principle active the trinitroglycerine.

The NO also has the property to inhibit the progress of the atheroma plaques, it is thus a factor antiatherogenic.

The NO also inhibits the formation of the clot responsible for the thrombosis. It is thus an inhibitive factor of the aggregation of plaques.

An arginine supply induces the production of the group NO and improves the vascular resistance.

• Taurine is also an amino acid but it contains in its structure a function thiol (-SH) able to reduce the free radicals of oxygen and picking up the heavy metals.

It is thus a sulfur amino acid antioxidant chelator of heavy metals.
The taurine is also an inhibitor of the angiotensin II, polypeptide vasoconstrictor known for its hypertensives properties.

But the taurine is also an amino acid involved in the elimination of the cholesterol by the biliary ways under the form of taurocholate. The taurine accelerates the metabolism of bad fats.

• The alpha-lipoic acid or thioctic acid is an anti-inflammatory and anti-radical powerful one at once liposoluble and hydrosoluble which also induce a vasorelaxant effect by increasing the production of NO by vascular endothelial cells .

The lipoic acid is also an activator of the cellular breath, which plays an essential role in the energy supply (in the form of ATP) at the muscular level and all the more at the level of the cardiac muscle.

It should be note that the lipoic acid can have an action on insulin resistance and from then on the glycemia.

This thioacide under its anti-oxidizing reduced form by these two groups -SH is also used since several years to treat neuropathy often observed in diabetics.

The lipoïc acid also increases the production of reduced glutathione to the arterial level and the article cited above shows that this cofactor also reduces the rate of triglycerides.

A recent article published in the British Newspaper of Pharmacology 2008,153, 1587-1588 describes the protective action of the acid lipoic on the smoother cells which line our vascular system.

The article describes the modes of action and the beneficial effects of the acid lipoic on the aortic rings of rats by the stimulation of synthesis of biochemical compounds physiologically active protecting us against the oxidation.

• The GSH or reduced glutathione is an anti-radical component essential to the metabolism of our cells.

The GSH is also a sensor of heavy metals and we have added it to our food complement to increase its bioavailability often worsened by pollutants such as heavy metals.

• The SOD or superoxide dismutase is an enzyme appearing under various forms found at the same time in the blood plasma and in all the compartments of our cells.

Its role is to neutralize the free radicals of oxygen by the formation of water by the glutathione peroxidase, provided that the reduced glutathione(GSH) is present and under an active form. What we have planned in our formulation.

So that this neutralization can be made in good conditions, three physiological elements are indispensable and that is why we added zinc, copper and manganese in our food supplement.

These three physiological metals accelerate the speed of the reaction of neutralization of the free radicals by the SOD.

Let us remind that pollutants such as the mercury and the cadmium, more and more present in our food, take the place of zinc, copper and manganese, so blocking the activity of the SOD.

Besides, the consumption of polyunsaturated fatty acids polyunsaturated of omega-3 type and certainly acids EPA and DHA (eicosapentanoic acid and docosahexaenoic acid) from fish oils decrease the incidence of the cardiovascular diseases.

These fatty acids are anti-thombotic.

The protective effect of omega-3 EPA and DHA is reached at doses between 500 mg and 900 mg a day.

The article " n-3 Fatty acids and cariovascular disease " published by Jan L.Breslow in American Journal of Nutrition 2006, 83, 1477-1482 demonstrate that from 3g/day making associations of EPA and DHA leads to a reduced risk of thrombosis, lower blood pressure and a marked improvement in vascular reactivity.

We shall add in these noticed that the EPA and the DHA are mediators of the inflammation and the regulators of the immunity.

Besides, American Heart Association recommends taking these two fatty acid omega-3 in food complement to reduce the risks of cardiovascular pathologies.